“I know one thing, that i know no-thing”
Introducing mutations into a gene and obtaining altered enzyme variants is simple. The true science is to discover an enzyme with the desired properties in the shortest possible timeframe at preferably marginal costs – and avoiding running in the wrong direction by aiming for unfeasible results.
In protein engineering there are numerous pitfalls along the way, in protein production, assay development, screening procedures, computational analysis, result evaluation and downstream processing. Interdependencies lead to scenarios where a decision in the protein production severly impedes proper protein purification and all steps in between have to be repeated.
With more than 20 years of combined protein engineering experience, SeSaM-Biotech offers first-class consulting services to prevent critical mistakes and lead your enzyme evolution project to success.