“I know one thing, that i know no-thing”

– Socrates

Introducing mutations into a gene and obtaining altered enzyme variants is simple. The true science is to discover an enzyme with the desired properties in the shortest possible timeframe at preferably marginal costs – and avoiding running in the wrong direction by aiming for unfeasible results.

In protein engineering there are numerous pitfalls along the way, in protein production, assay development, screening procedures, computational analysis, result evaluation and downstream processing. Interdependencies lead to scenarios where a decision in the protein production severly impedes proper protein purification and all steps in between have to be repeated.

With more than 20 years of combined protein engineering experience, SeSaM-Biotech offers first-class consulting services to prevent critical mistakes and lead your Directed Enzyme Evolution project to success.


Interested in our consulting packages?

Consulting as part of the QuESt-service


In our all-in-one service package “QuESt”, we do not blindly follow the strategy outlined in our quotes. It is not uncommon in R&D projects that the strategy, goals and timeframes are subject to sudden changes. We regularly consult with our clients during the entire Directed Evolution project, discuss results together, provide recommendations based on our expertise and jointly decide about the most promising strategies to ensure all demands are met and to quickly adapt to any changes necessary.


Learn more about QuESt here or get in touch with us to hire Directed Evolution expertise for your project.