QuESt – short for Quality Enzyme Solutions – is our all-in-one solution to give your enzymes the competitive advantage. We can enhance every property of your enzyme, including enzymatic activity, thermal resilience, solvent stability, pH resistance, substrate specificity product spectrum, removing inhibitory effects and more. Our track record spans more than 30 enzymes and assays including lipases, proteases, polymerases, laccases, monooxygenases, reductases, sugar isomerases, cellulases, phytases, pectinases, glucose oxidases, amylases and alcohol dehydrogenases that are expressed and screened in our four expression platforms E. coli, B. subtilis, S. cerevisiae and P. pastoris.
QuESt employs our protein engineering strategy “KnowVolution” – a knowledge-gaining directed enzyme evolution. KnowVolution is a combined approach of random and rational enzyme evolution, compensating the disadvantages of purely random or purely rational (computational) evolution strategies. As a result, we achieved both a high cost efficiency and increased success chances.